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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CREBBP
All Species:
24.24
Human Site:
S331
Identified Species:
44.44
UniProt:
Q92793
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92793
NP_001073315.1
2442
265351
S331
N
M
S
Q
M
Q
T
S
V
G
I
V
P
T
Q
Chimpanzee
Pan troglodytes
XP_523285
2442
265358
S331
N
M
S
Q
M
Q
T
S
V
G
I
V
P
T
Q
Rhesus Macaque
Macaca mulatta
XP_001095225
2442
265320
S331
N
M
S
Q
M
Q
T
S
V
G
I
V
P
T
Q
Dog
Lupus familis
XP_851777
2404
260682
S331
N
M
S
Q
M
Q
T
S
V
G
I
V
P
T
Q
Cat
Felis silvestris
Mouse
Mus musculus
P45481
2441
265456
S330
N
M
S
Q
L
Q
T
S
V
G
I
V
P
T
Q
Rat
Rattus norvegicus
NP_596872
2444
265618
S330
N
M
S
Q
L
Q
T
S
V
G
I
V
P
A
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414964
2447
266615
Q317
N
M
S
Q
M
Q
T
Q
V
Q
Q
V
G
I
V
Frog
Xenopus laevis
NP_001088637
2428
264402
V324
N
M
A
Q
V
Q
Q
V
G
I
G
T
T
P
S
Zebra Danio
Brachydanio rerio
NP_001082924
2111
234059
M253
Q
T
P
H
Q
Q
P
M
R
S
I
N
A
L
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524642
3276
340709
M421
G
N
P
Q
Q
Q
Q
M
L
A
Q
Q
Q
T
G
Honey Bee
Apis mellifera
XP_001122031
2606
284119
S337
N
M
G
Q
I
G
A
S
S
P
Y
Y
G
S
P
Nematode Worm
Caenorhab. elegans
P34545
2056
227161
H198
Q
Q
F
P
G
M
M
H
R
Y
P
Y
A
Q
G
Sea Urchin
Strong. purpuratus
XP_782558
2635
288594
N401
M
P
G
N
M
N
I
N
P
N
N
M
G
S
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
99.4
93.9
N.A.
94.8
95.8
N.A.
N.A.
88
76
61.5
N.A.
36.5
42.7
30.5
38.5
Protein Similarity:
100
99.9
99.6
95.5
N.A.
96.4
97.2
N.A.
N.A.
92
83.3
68.8
N.A.
46.7
54.7
43.9
50.9
P-Site Identity:
100
100
100
100
N.A.
93.3
86.6
N.A.
N.A.
60
26.6
13.3
N.A.
20
26.6
0
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
93.3
N.A.
N.A.
60
40
13.3
N.A.
26.6
40
0
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
8
0
0
8
0
0
16
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
16
0
8
8
0
0
8
47
8
0
24
0
24
% G
% His:
0
0
0
8
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
0
8
0
0
8
54
0
0
8
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
16
0
0
0
8
0
0
0
0
8
0
% L
% Met:
8
70
0
0
47
8
8
16
0
0
0
8
0
0
0
% M
% Asn:
70
8
0
8
0
8
0
8
0
8
8
8
0
0
0
% N
% Pro:
0
8
16
8
0
0
8
0
8
8
8
0
47
8
16
% P
% Gln:
16
8
0
77
16
77
16
8
0
8
16
8
8
8
47
% Q
% Arg:
0
0
0
0
0
0
0
0
16
0
0
0
0
0
0
% R
% Ser:
0
0
54
0
0
0
0
54
8
8
0
0
0
16
8
% S
% Thr:
0
8
0
0
0
0
54
0
0
0
0
8
8
47
0
% T
% Val:
0
0
0
0
8
0
0
8
54
0
0
54
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
8
16
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _